The INTS1 Polyclonal Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to INTS1. This antibody recognizes Human, Mouse, and Rat antigen. The INTS1 Polyclonal Antibody has been validated for the following applications: ELISA, and Immunohistochemistry.
Description
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit and mediates 3-prime end processing of small nuclear RNAs U1 and U2. RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin